MUSCLE MASS NOT LEAN MASS IS ASSOCIATED WITH HEALTH-RELATED OUTCOMES: IMPLICATIONS FOR DEFINING SARCOPENIA
2024
Muscle Mass and Health Outcomes in Older Men
Sample size: 1400
publication
Evidence: high
Author Information
Author(s): Cawthon Peggy
Primary Institution: California Pacific Medical Center, San Francisco, California, United States
Hypothesis
Low D3Cr muscle mass is associated with worse health-related outcomes in older men.
Conclusion
Low D3Cr muscle mass is linked to worse physical performance and higher risk of health issues in older men.
Supporting Evidence
- Low D3Cr muscle mass was associated with worse Short Physical Performance Battery scores.
- Men with higher D3Cr muscle mass had lower prevalence of type 2 diabetes and other chronic diseases.
- Low D3Cr muscle mass was linked to increased risk of hip fractures and mortality over 3-5 years.
Takeaway
Having less muscle mass can make older men weaker and more likely to have health problems.
Methodology
The study used the D3Cr dilution method to assess muscle mass in older men.
Participant Demographics
Older men with a mean age of 84.2 years, reporting multiple chronic diseases.
Digital Object Identifier (DOI)
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