Breast Cancer in Chinese Women: A 10-Year Study
Author Information
Author(s): Li Jing, Zhang Bao-Ning, Fan Jin-Hu, Pang Yi, Zhang Pin, Wang Shu-Lian, Zheng Shan, Zhang Bin, Yang Hong-Jian, Xie Xiao-Ming, Tang Zhong-Hua, Li Hui, Li Jia-Yuan, He Jian-Jun, Qiao You-Lin
Primary Institution: Cancer Institute & Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
Hypothesis
What is the profile and treatment approach for female breast cancer in China over a 10-year period?
Conclusion
The study highlights the younger age of breast cancer onset and the need for improved treatment options in China.
Supporting Evidence
- 60.6% of patients had early stage breast cancer.
- Radical mastectomy was the most common treatment, performed on 88.8% of patients.
- 25.8% of patients tested positive for HER-2.
- 47.9% of patients were positive for both estrogen and progestin receptors.
- Breast cancer incidence is increasing in metropolitan areas of China.
- Patients in late stage were more likely to be manual workers.
- Mean age at diagnosis was 48.7 years.
Takeaway
This study looked at breast cancer in Chinese women over 10 years and found that many women are diagnosed at a younger age and need better treatment options.
Methodology
A hospital-based multi-center retrospective study reviewing inpatient cases of primary breast cancer from 1999 to 2008 across seven regions in China.
Potential Biases
Data quality is dependent on clinician documentation, which may vary.
Limitations
Selection bias may exist due to the choice of hospitals and lack of a comparison group.
Participant Demographics
The mean age at diagnosis was 48.7 years, with a range from 21 to 86 years.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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