Are benefits and harms in mammography screening given equal attention in scientific articles? A cross-sectional study
2007

Imbalance in Reporting Benefits and Harms of Mammography Screening

Sample size: 143 publication Evidence: moderate

Author Information

Author(s): Jørgensen Karsten Juhl, Klahn Anders, Gøtzsche Peter C

Primary Institution: The Nordic Cochrane Centre, Department 3343, Rigshospitalet

Hypothesis

Is there an imbalance in the reporting of benefits and harms in scientific articles on mammography screening related to author affiliation?

Conclusion

Scientific articles tend to emphasize the major benefits of mammography screening over its major harms, and this imbalance is related to the authors' affiliation.

Supporting Evidence

  • 96% of articles mentioned benefits while only 62% mentioned harms.
  • 38% of articles mentioned only benefits, and 5% mentioned only harms.
  • Authors working with screening were more likely to downplay overdiagnosis.

Takeaway

This study found that articles about mammography screening talk more about the good things than the bad things, especially if the authors are involved in screening.

Methodology

The study involved a cross-sectional analysis of articles on mammography screening published in 2004, focusing on the mention of benefits and harms.

Potential Biases

Authors working with screening were less likely to acknowledge harms, indicating potential bias.

Limitations

The study may not capture all articles on the topic, and some author affiliations were unclear.

Statistical Information

P-Value

P < 0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1741-7015-5-12

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