Automated Polarograph for Analyzing Labile Compounds
Author Information
Author(s): R. E. Cooley, C. E. Stevenson, E. C. Rickard
Primary Institution: The Lilly Research Laboratories, Eli Lilly and Company
Hypothesis
The automation of polarography can improve efficiency and accuracy in analyzing solution labile compounds.
Conclusion
The automated polarograph significantly increases throughput and precision compared to manual methods.
Supporting Evidence
- The automated system can assay 40 samples per day with three scans each.
- The precision of the automated system was found to be better than 1.6%.
- The carryover contamination was only 0.05% in the blank vial.
Takeaway
This study shows that using a robot to help analyze samples can make the process faster and more accurate.
Methodology
The study involved developing an automated polarographic system and comparing its performance with manual procedures.
Potential Biases
Potential carryover contamination between samples due to the sampler head not being rinsed.
Limitations
The study did not evaluate the accuracy of the volume delivered by dispensers, only their precision.
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