Effect of dairy fat on plasma phytanic acid in healthy volunteers - a randomized controlled study
2011

Impact of Dairy Fat on Phytanic Acid Levels in Healthy People

Sample size: 14 publication 10 minutes Evidence: moderate

Author Information

Author(s): Werner Louise B, Hellgren Lars I, Raff Marianne, Jensen Søren K, Petersen Rikke A, Drachmann Tue, Tholstrup Tine

Primary Institution: Department of Human Nutrition, Faculty of Life, University of Copenhagen

Hypothesis

Does cow feeding regimes affect plasma phytanic acid concentration and metabolic syndrome risk markers in humans?

Conclusion

Increased intake of dairy fat modifies plasma phytanic acid concentration, but does not significantly affect metabolic syndrome risk markers.

Supporting Evidence

  • Plasma phytanic acid increased significantly within both groups after the dietary intervention.
  • The control group had a higher increase in plasma phytanic acid compared to the phytanic acid group.
  • No significant effects were observed on metabolic syndrome risk markers.

Takeaway

Eating more dairy fat can change the amount of phytanic acid in your blood, but it doesn't seem to help with health issues like diabetes.

Methodology

A double-blind, randomized, 4-week study with 14 healthy subjects consuming different dairy fats.

Potential Biases

Higher baseline phytanic acid levels in the control group may have influenced results.

Limitations

Small sample size and potential dietary confounding factors.

Participant Demographics

14 healthy young adults, aged 20 to 42, with a mix of genders.

Statistical Information

P-Value

0.0730

Statistical Significance

p=0.0730

Digital Object Identifier (DOI)

10.1186/1476-511X-10-95

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