Functionalization of heterocyclic compounds using polyfunctional magnesium and zinc reagents
2011
Functionalization of Heterocyclic Compounds with Magnesium and Zinc Reagents
publication
Evidence: high
Author Information
Author(s): Knochel Paul, Schade Matthias A, Bernhardt Sebastian, Manolikakes Georg, Metzger Albrecht, Piller Fabian M, Rohbogner Christoph J, Mosrin Marc, Snieckus Victor
Primary Institution: Ludwig-Maximilians-Universität München
Conclusion
The review summarizes important procedures for preparing functionalized organozinc and organomagnesium reagents, highlighting their significance in organic synthesis.
Supporting Evidence
- The review highlights the importance of functionalized magnesium and zinc reagents in pharmaceutical research.
- New methods for preparing polyfunctional aryl- and heteroaryl zinc and magnesium compounds are discussed.
- Experimental details for the most important reactions are provided in the Supporting Information.
Takeaway
This study talks about how to make special chemical compounds using magnesium and zinc, which are important for creating new medicines.
Methodology
The review discusses various methods for preparing functionalized organozinc and organomagnesium reagents, including new Pd-catalyzed cross-coupling reactions.
Digital Object Identifier (DOI)
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