Nationwide Investigation of the Pyrethroid Susceptibility of Mosquito Larvae Collected from Used Tires in Vietnam
2009

Mosquito Resistance to Pyrethroids in Vietnam

Sample size: 19188 publication 10 minutes Evidence: high

Author Information

Author(s): Kawada Hitoshi, Higa Yukiko, Nguyen Yen T., Tran Son H., Nguyen Hoa T., Takagi Masahiro

Primary Institution: Institute of Tropical Medicine, Nagasaki University

Hypothesis

The study investigates the susceptibility of mosquito larvae to pyrethroids collected from used tires in Vietnam.

Conclusion

Aedes aegypti showed significant resistance to d-allethrin, particularly in southern Vietnam, likely due to extensive pyrethroid use for malaria control.

Supporting Evidence

  • Aedes aegypti showed the most prominent reduction in susceptibility to d-allethrin compared to other species.
  • Significant increases in susceptibility indices were observed with a decrease in latitude.
  • The study collected larvae from 527 points across Vietnam, indicating a wide geographical scope.

Takeaway

The study found that mosquitoes in Vietnam, especially Aedes aegypti, are becoming less sensitive to a common insecticide because it has been used a lot in the area.

Methodology

Mosquito larvae were collected from used tires along national roads and tested for susceptibility to d-allethrin using a simplified bioassay.

Potential Biases

Potential bias due to the selection of collection sites along roads, which may not reflect broader ecological conditions.

Limitations

The study was limited to larvae collected from used tires and may not represent all mosquito populations in Vietnam.

Participant Demographics

The study focused on three mosquito species: Aedes aegypti, Aedes albopictus, and Culex quinquefasciatus.

Statistical Information

P-Value

p<0.0001

Statistical Significance

p<0.0001

Digital Object Identifier (DOI)

10.1371/journal.pntd.0000391

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