Incidence, organ dysfunction and mortality in severe sepsis: a Spanish multicentre study

2008

Incidence and Outcomes of Severe Sepsis in Spain

Sample size: 2619 publication Evidence: high

Author Information

Author(s): Blanco Jesús, Muriel-Bombín Arturo, Sagredo Víctor, Taboada Francisco, Gandía Francisco, Tamayo Luís, Collado Javier, García-Labattut Ángel, Carriedo Demetrio, Valledor Manuel, De Frutos Martín, López María-Jesús, Caballero Ana, Guerra José, Álvarez Braulio, Mayo Agustín, Villar Jesús

Primary Institution: Critical Care Department, Nuevo Hospital Universitario Río Hortega, Valladolid, Spain

Hypothesis

What is the incidence of severe sepsis among adults in ICUs in Spain and what are the associated mortality rates?

Conclusion

The study found a high incidence of severe sepsis in the ICU and high mortality rates, indicating potential delays in diagnosis and treatment.

Supporting Evidence

The estimated accumulated incidence for the population was 25 cases of severe sepsis per 100,000 inhabitants per year.
54.3% of patients died in the hospital, with 48.2% of these deaths occurring in the ICU.
78.1% of patients had two or more organ failures at diagnosis.

Takeaway

This study looked at how many people get very sick from sepsis in hospitals in Spain and found that a lot of them die, especially if they have other health problems.