Surgical Treatment of Perforated Peptic Ulcers in Tanzania
Author Information
Author(s): Chalya Phillipo L, Mabula Joseph B, Koy Mheta, Mchembe Mabula D, Jaka Hyasinta M, Kabangila Rodrick, Chandika Alphonce B, Gilyoma Japhet M
Primary Institution: Weill-Bugando University College of Health Sciences
Hypothesis
This study aims to evaluate the clinical presentation, management, and outcomes of patients with perforated peptic ulcers in Northwestern Tanzania.
Conclusion
Perforation of peptic ulcer is a common issue in our area, mainly affecting young males, and simple closure with omental patch followed by H. pylori eradication was effective in most cases despite late presentations.
Supporting Evidence
- The study included 84 patients, with a male to female ratio of 1.3:1.
- Complications occurred in 29.8% of patients, with a mortality rate of 10.7%.
- Most perforations were located in the duodenum (90.4%).
- Graham's omental patch was performed in 83.3% of cases.
Takeaway
Doctors in Tanzania found that many young men get serious stomach problems from ulcers, but a simple surgery helped most of them feel better.
Methodology
This was a combined retrospective and prospective study of patients operated for perforated peptic ulcers at Bugando Medical Centre from April 2006 to March 2011.
Potential Biases
Potential bias due to exclusion of patients with incomplete data and those who did not consent for HIV testing.
Limitations
The study may not fully represent outcomes after laparoscopic repair, and the association of H. pylori with postoperative outcomes was not studied due to lack of facilities.
Participant Demographics
The majority of participants were young males, with a median age of 28 years, and many had no previous history of peptic ulcer disease.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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