HPV and Cervical Abnormalities in HIV-Positive Women
Author Information
Author(s): Dames Dionne N, Ragin Camille, Griffith-Bowe Andrea, Gomez Perry, Butler Raleigh
Primary Institution: Princess Margaret Hospital, Nassau, Bahamas
Hypothesis
What is the prevalence of high-risk HPV genotypes and cervical dysplasia in HIV sero-positive females in the Bahamas?
Conclusion
The study found a high prevalence of high-risk HPV and cervical abnormalities among HIV-sero positive females, indicating a need for regular screening.
Supporting Evidence
- 67% of participants tested positive for high-risk HPV.
- 44% of participants had cervical abnormalities.
- 97% of women with cervical cytology abnormalities were HPV positive.
Takeaway
This study shows that many women with HIV also have a virus called HPV that can cause cervical cancer, so they need to get checked regularly.
Methodology
One hundred HIV-sero-positive females were screened for high-risk HPV infections and cervical cytology abnormalities using liquid-based pap smear and HPV detection methods.
Potential Biases
Potential bias due to the small sample size and lack of control group.
Limitations
The study could not compare results with HIV-sero-negative women due to lack of data.
Participant Demographics
Participants were mostly Bahamian women aged 20-71, with a mean age of 40.1 years.
Statistical Information
P-Value
0.001
Confidence Interval
95% CI: 0.05 – 0.8
Statistical Significance
p = 0.001
Digital Object Identifier (DOI)
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