Calorie restriction and stroke
2011

Calorie Restriction and Stroke

publication Evidence: moderate

Author Information

Author(s): Silvia Manzanero, Mathias Gelderblom, Tim Magnus, Thiruma V Arumugam

Hypothesis

Can dietary energy restriction protect against stroke-induced brain injury?

Conclusion

Calorie restriction may help protect the brain from stroke by activating various neuroprotective mechanisms.

Supporting Evidence

  • Calorie restriction has been shown to extend lifespan and reduce age-related diseases in animal models.
  • Studies suggest that calorie restriction can protect neurons against dysfunction and degeneration.
  • Calorie restriction may reduce oxidative stress and inflammation, which are linked to stroke.
  • Neurotrophic factors like BDNF are upregulated by calorie restriction, promoting brain health.
  • Calorie restriction can improve cardiovascular health, reducing stroke risk.

Takeaway

Eating less can help your brain stay healthy and protect it from getting hurt during a stroke.

Methodology

The article reviews findings from various studies on the effects of calorie restriction and intermittent fasting on stroke and brain health.

Limitations

The evidence primarily comes from animal studies, and the effects in humans are less clear.

Digital Object Identifier (DOI)

10.1186/2040-7378-3-8

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