Acute Hemorrhagic Conjunctivitis Due to Enterovirus 70 in India
1999

Acute Hemorrhagic Conjunctivitis Due to Enterovirus 70 in India

Sample size: 13 publication Evidence: high

Author Information

Author(s): R.S. Maitreyi, L. Dar, A. Muthukumar, M. Vajpayee, I. Xess, R.B. Vajpayee, P. Seth, S. Broor

Primary Institution: All India Institute of Medical Sciences, New Delhi, India

Hypothesis

What is the etiologic agent of the outbreak of acute hemorrhagic conjunctivitis in Delhi, India?

Conclusion

The outbreak of acute hemorrhagic conjunctivitis was confirmed to be caused by enterovirus type 70.

Supporting Evidence

  • 10 of the 13 clinical samples showed specific cytoplasmic fluorescence with monoclonal antibodies to EV-70.
  • All 10 clinical isolates were neutralized by EV-70 specific antisera.
  • PCR was positive for EV-70 in 11 of the 13 cases.

Takeaway

A group of people in India got a type of eye infection caused by a virus called enterovirus 70, and doctors figured it out using special tests.

Methodology

The study involved enrolling patients, taking conjunctival swabs, and using viral culture, immunofluorescence, neutralization tests, and PCR to identify the virus.

Participant Demographics

9 male and 4 female patients, ages 14 to 37 years.

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