Littoral Cell Angioma of the Spleen in a Patient with Pulmonary Sarcoidosis
Author Information
Author(s): Cordesmeyer Stefanie, Pützler Manfred, Titze Ulf, Paulus Harald, Hoffmann Matthias W
Primary Institution: University Hospital, Münster, Germany
Hypothesis
Is there a TNF-α related pathogenesis for littoral cell angioma in patients with immune dysregulation?
Conclusion
Littoral cell angioma is a rare splenic tumor that may be associated with immune dysregulation and previous malignancies.
Supporting Evidence
- Littoral cell angioma is a rare vascular tumor of the spleen.
- About one-third of reported cases are associated with malignancies or immune-mediated diseases.
- The patient had a history of pulmonary sarcoidosis treated with corticosteroids.
Takeaway
A man had a rare tumor in his spleen that might be linked to his past lung disease, and doctors think it could be related to his immune system acting up.
Methodology
The patient underwent a laparoscopic splenectomy for diagnosis after imaging suggested lymphoma.
Limitations
The study is based on a single case report, limiting generalizability.
Participant Demographics
43-year-old male with a history of pulmonary sarcoidosis.
Digital Object Identifier (DOI)
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