Silent cerebral infarct after cardiac catheterization as detected by diffusion weighted Magnetic Resonance Imaging: a randomized comparison of radial and femoral arterial approaches
2007

Silent Cerebral Infarct After Cardiac Catheterization: Comparing Radial and Femoral Approaches

Sample size: 152 publication Evidence: moderate

Author Information

Author(s): Hamon Michèle, Burzotta Francesco, Oppenheim Catherine, Morello Rémy, Viader Fausto, Hamon Martial

Primary Institution: University Hospital of Caen, Normandy, France

Hypothesis

What is the rate of silent cerebral infarction after cardiac catheterization, and how does the arterial access site affect this rate?

Conclusion

The study aims to assess the occurrence of silent cerebral infarction after cardiac catheterization and compare the effects of radial versus femoral access.

Supporting Evidence

  • Cerebral microembolism occurs during cardiac catheterization.
  • Asymptomatic embolic cerebral infarction might occur in 15 to 22% of cases.
  • The study will use diffusion-weighted MRI to assess silent cerebral infarction.

Takeaway

Doctors want to find out if using different entry points for heart procedures can cause hidden brain injuries.

Methodology

This is a prospective multicenter randomized trial involving patients with severe aortic valve stenosis who will undergo DW-MRI and neurological assessments before and after cardiac catheterization.

Limitations

Exclusion criteria include contraindications to MRI or inability to give informed consent.

Participant Demographics

Patients with severe aortic stenosis scheduled for cardiac catheterization.

Statistical Information

Confidence Interval

5.9% [0.01–12.5; 95% CI] for radial approach; 23% [15–31; 95% CI] for femoral approach.

Digital Object Identifier (DOI)

10.1186/1745-6215-8-15

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