Evaluating Tono-Pen XL for Measuring Eye Pressure in Rabbits
Author Information
Author(s): Charisis Spyridon K, Ginis Harilaos S, Kounis Georgios A, Tsilimbaris Miltiadis K
Primary Institution: University Hospital of Heraklion, Eye Clinic, Heraklion, Crete, Greece
Hypothesis
The study aims to evaluate the accuracy of Tono-Pen XL in measuring intraocular pressure (IOP) during the application of a suction ring in rabbit eyes.
Conclusion
Tono-Pen XL measurements are unreliable during the application of a suction ring on living rabbit eyes.
Supporting Evidence
- Tono-Pen XL was calibrated against direct manometry in 10 rabbit eyes.
- Linear regression analysis showed Tono-Pen XL is reliable for IOPs between 10 and 70 mmHg.
- Measurements indicated no statistically significant variation of Tono-Pen XL readings during suction ring application.
Takeaway
The Tono-Pen XL, a device used to measure eye pressure, doesn't work well when a suction ring is applied to a rabbit's eye.
Methodology
Tono-Pen XL was calibrated against direct manometry in 10 rabbit eyes, and IOP was measured during suction ring application at various pressures.
Potential Biases
Potential bias due to the small sample size and the specific conditions of the experiments.
Limitations
The study's findings may not be applicable to humans due to anatomical differences between rabbits and humans.
Participant Demographics
Healthy albino rabbits weighing between 3 and 4 Kg.
Statistical Information
Statistical Significance
p>0.05
Digital Object Identifier (DOI)
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