A Model Framework to Estimate Impact and Cost of Genetics-Based Sterile Insect Methods for Dengue Vector Control
2011

Using Genetic Control to Fight Dengue Fever

publication Evidence: moderate

Author Information

Author(s): Alphey Nina, Alphey Luke, Bonsall Michael B.

Primary Institution: University of Oxford

Hypothesis

Can genetic vector control methods effectively reduce dengue transmission and costs compared to traditional methods?

Conclusion

The study suggests that genetic control strategies could eliminate dengue at a lower cost than the direct and indirect costs of the disease.

Supporting Evidence

  • The genetic control strategy could eliminate dengue rapidly from a human community.
  • The cost-effectiveness of genetic vector control is significantly lower than the costs associated with dengue cases.
  • Current methods of dengue control are costly and often ineffective.

Takeaway

Scientists are trying to use special mosquitoes to stop dengue fever from spreading, and it might be cheaper than other ways to control the disease.

Methodology

The study used mathematical models to simulate the impact of releasing genetically modified mosquitoes on dengue transmission and cost-effectiveness.

Potential Biases

Potential conflicts of interest due to funding from companies involved in genetic control technologies.

Limitations

The model simplifies many real-world factors and may not accurately predict outcomes in specific settings.

Digital Object Identifier (DOI)

10.1371/journal.pone.0025384

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