Review of Treatments for Posthaemorrhagic Hydrocephalus in Infants
Author Information
Author(s): Shooman David, Portess Howard, Sparrow Owen
Primary Institution: Wessex Neurological Centre, Southampton General Hospital
Hypothesis
What are the current treatment methods for posthaemorrhagic hydrocephalus (PHH) in infants?
Conclusion
There is currently no definitive treatment for posthaemorrhagic hydrocephalus, and many existing treatments have significant risks and limitations.
Supporting Evidence
- Current treatments for PHH include lumbar punctures and diuretics, but they often fail to prevent shunt dependence.
- Postnatal phenobarbital has not been shown to prevent intraventricular hemorrhage.
- New therapeutic approaches are needed to improve outcomes for infants with PHH.
Takeaway
Doctors are trying to find the best ways to help babies with a serious condition called posthaemorrhagic hydrocephalus, but many treatments don't work well and can cause problems.
Methodology
The review analyzed literature from the Cochrane Central Register of Controlled Trials and PubMed, focusing on trials involving infants under 12 months with PHH.
Potential Biases
The review may be limited by the quality and scope of the studies included, as well as potential publication bias.
Limitations
The review highlights that many treatments have not been tested in randomized controlled trials and that there is no consensus on effective management.
Participant Demographics
Infants less than 12 months old with posthaemorrhagic hydrocephalus.
Digital Object Identifier (DOI)
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