Regeneration of the radial nerve cord in the sea cucumber Holothuria glaberrima
2009

Regeneration of the radial nerve cord in the sea cucumber

publication 10 minutes Evidence: moderate

Author Information

Author(s): San Miguel-Ruiz José E, Maldonado-Soto Angel R, García-Arrarás José E

Primary Institution: University of Puerto Rico, Rio Piedras

Hypothesis

Can the sea cucumber Holothuria glaberrima regenerate its radial nerve cord after transection?

Conclusion

Holothuria glaberrima can regenerate its radial nerve cord within a month, achieving a structure similar to the uninjured cord.

Supporting Evidence

  • H. glaberrima can regenerate its radial nerve cord within a month following transection.
  • The regenerated cord resembles the uninjured cord in morphology and cellular composition.
  • Cellular events during regeneration include nerve fiber outgrowth and intense cellular division.

Takeaway

Sea cucumbers can heal their nerve cords after being cut, and they do it pretty quickly, like magic!

Methodology

The radial nerve cord was transected, and regeneration was analyzed over 28 days using histological techniques and immunohistochemistry.

Limitations

The study primarily focuses on one species and may not generalize to all echinoderms.

Participant Demographics

Holothuria glaberrima specimens, 10–16 cm long, collected from Puerto Rico.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-213X-9-3

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