Effects of Combined Treatment on Neurological Function in Acute Progressive Cerebral Infarction
Author Information
Author(s): Li Yaqiang, Liu Jie, Zhu Yuanyuan, Xue Min, He Jiale
Primary Institution: First Affiliated Hospital of Anhui University of Science and Technology
Hypothesis
Does the combination of butylphthalide sodium chloride injection and edaravone dexborneol improve neurological function and reduce inflammatory factors in patients with acute progressive cerebral infarction?
Conclusion
The combination treatment significantly improves neurological function and reduces inflammatory factors in patients with acute progressive cerebral infarction.
Supporting Evidence
- The observation group had a higher effective rate of 89% compared to 65% in the control group.
- Significant improvements in NIHSS and Barthel index scores were observed in the observation group.
- Levels of inflammatory factors decreased more significantly in the observation group than in the control group.
Takeaway
This study shows that using two medicines together can help people with a serious brain problem feel better and have less inflammation.
Methodology
200 patients with acute progressive cerebral infarction were randomly divided into a control group and an observation group, receiving different treatments for 14 days, with various neurological and inflammatory factors measured before and after treatment.
Potential Biases
Potential bias in patient selection and treatment allocation.
Limitations
The study was limited to a single hospital and may not be generalizable to all populations.
Participant Demographics
200 patients aged 40-80, with a mix of genders and various vascular risk factors.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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