Comparing COI and ITS as DNA Barcode Markers for Mushrooms and Allies (Agaricomycotina)
2011

Comparing DNA Markers for Identifying Mushrooms

Sample size: 167 publication Evidence: moderate

Author Information

Author(s): Bryn T. M. Dentinger, Maryna Y. Didukh, Jean-Marc Moncalvo

Primary Institution: University of Toronto

Hypothesis

Is the mitochondrial cytochrome oxidase I gene (COI) an effective DNA barcode for mushrooms compared to the internal transcribed spacer (ITS) regions?

Conclusion

The study concludes that COI is less effective than ITS for barcoding mushrooms due to the presence of large introns and lower divergence.

Supporting Evidence

  • 167 partial COI sequences were generated from approximately 100 morphospecies.
  • COI and ITS performed similarly for some taxa, but COI was less divergent overall.
  • Large introns were found in about 5% of the COI sequences, affecting PCR success.

Takeaway

Scientists wanted to find out which part of DNA works best to tell different types of mushrooms apart, and they found that one part (ITS) is better than another (COI).

Methodology

The study involved collecting mushroom specimens, extracting DNA, and comparing the effectiveness of COI and ITS as DNA barcoding markers.

Limitations

The study faced challenges with low PCR success rates for COI due to large introns and the inability to design universal primers for all mushrooms.

Digital Object Identifier (DOI)

10.1371/journal.pone.0025081

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