Spiral-Wave Turbulence and Its Control in the Presence of Inhomogeneities in Four Mathematical Models of Cardiac Tissue
2009

Controlling Spiral-Wave Turbulence in Cardiac Tissue Models

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Author Information

Author(s): Shajahan T. K., Nayak Alok Ranjan, Pandit Rahul

Primary Institution: Indian Institute of Science, Bangalore, India

Hypothesis

The dynamics of spiral waves in cardiac tissue models depend sensitively on inhomogeneities.

Conclusion

The study confirms that spiral-wave dynamics are significantly affected by the presence and position of inhomogeneities in cardiac tissue models.

Supporting Evidence

  • Spiral-wave dynamics are sensitive to the position of conduction and ionic inhomogeneities.
  • Low-amplitude control schemes can effectively suppress spiral-wave turbulence.
  • The study provides insights into the mechanisms of cardiac arrhythmias.

Takeaway

This study looks at how irregularities in heart tissue can change the way heart waves behave, which is important for understanding heart problems.

Methodology

The study used numerical simulations of four mathematical models of cardiac tissue to analyze spiral-wave dynamics and control schemes.

Limitations

The study primarily focuses on two-dimensional simulations and does not fully explore three-dimensional models or bidomain models.

Digital Object Identifier (DOI)

10.1371/journal.pone.0004738

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