A compact automated microprocessor-based stopped-flow analyser
1980

Automated Microprocessor-Based Stopped-Flow Analyser

publication Evidence: high

Author Information

Author(s): Michael A. Koupparis, Ken M. Walczak, Howard V. Malmstadt

Primary Institution: School of Chemical Sciences, University of Illinois at Urbana-Champaign

Conclusion

The compact stopped-flow autoanalyzer can be used for both equilibrium and reaction rate methods with high accuracy and precision.

Supporting Evidence

  • The system demonstrated high precision with a relative standard deviation of 0.08% for dye dilution.
  • Results showed a correlation coefficient of 0.9994 for ascorbic acid determination.
  • The method for phosphorus determination achieved a correlation coefficient of 0.9998.
  • Creatinine determination yielded a correlation coefficient of 0.9994.
  • Glucose determination showed a correlation coefficient of 0.9997.

Takeaway

This machine mixes chemicals really fast to help scientists measure things accurately, like how much sugar is in a drink.

Methodology

The system uses a microcomputer to control the mixing and measurement of chemical reactions, allowing for rapid data acquisition and analysis.

Limitations

The system may not be suitable for very fast reactions with half-lives less than 200 milliseconds.

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