Impact of steroid hormone signals on Drosophila cell cycle during development
2009
Impact of Steroid Hormones on Drosophila Development
publication
10 minutes
Evidence: moderate
Author Information
Author(s): Cranna Nicola, Quinn Leonie
Primary Institution: University of Melbourne
Hypothesis
How do steroid hormone signals influence the cell cycle during Drosophila development?
Conclusion
The ecdysone pathway modulates cell cycle progression in Drosophila by regulating mitogenic pathways.
Supporting Evidence
- Ecdysone is essential for the removal of larval tissues during metamorphosis.
- Ecdysone signaling is linked to the activation of key cell cycle genes.
- The ecdysone pathway interacts with insulin signaling to control growth.
- Ecdysone regulates the transcription factor Crol, which affects cell cycle progression.
Takeaway
Ecdysone, a steroid hormone, helps Drosophila grow and develop by controlling when cells divide and change into different types.
Methodology
The study reviews existing literature and integrates evidence linking ecdysone signaling to cell cycle regulation.
Limitations
The study primarily relies on existing literature and may not include new experimental data.
Statistical Information
P-Value
0.0038
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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