Serum 25-hydroxyvitamin D is not related to cardiac natriuretic peptide in nulliparous and lactating women
2009

Vitamin D and Heart Health in Women

Sample size: 178 publication 10 minutes Evidence: moderate

Author Information

Author(s): Saadi Hussein F, Gary Nicholls M, Christopher M Frampton, Sheela Benedict, Javed Yasin

Primary Institution: UAE University

Hypothesis

What is the relationship between vitamin D levels and cardiac natriuretic peptide in nulliparous and lactating women?

Conclusion

There were no significant correlations between vitamin D levels and cardiac natriuretic peptide in the studied women.

Supporting Evidence

  • Vitamin D levels were low in most women studied.
  • NT-proBNP levels were within the normal range.
  • Vitamin D supplementation did not significantly change NT-proBNP levels.

Takeaway

The study looked at how vitamin D affects heart health in women who haven't had children and those who are breastfeeding, but found no clear link.

Methodology

The study measured vitamin D and cardiac markers in women before and after vitamin D supplementation.

Potential Biases

Potential bias due to lack of time-matched controls and low vitamin D levels in all subjects.

Limitations

The study lacked a control group and did not assess cardiac structure changes.

Participant Demographics

88 nulliparous Emirati women and 90 lactating women, mostly Arab and South Asian.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1472-6823-9-4

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