Fat Distribution and Liver Fat in Overweight Women
Author Information
Author(s): Paulo M. Rocha, José T. Barata, Cláudia S. Minderico, Analiza M. Silva, Pedro J. Teixeira, Luís B. Sardinha
Primary Institution: Exercise and Health Laboratory, Faculty of Human Movement, Technical University of Lisbon
Hypothesis
What are the associations between different fat compartments and liver fat in overweight and obese premenopausal women?
Conclusion
The study found that larger visceral fat is associated with increased liver fat, while thigh subfascial fat is inversely related to liver fat.
Supporting Evidence
- A larger visceral adipose tissue was related to increased liver fat.
- Thigh subfascial adipose tissue was inversely related to liver fat.
- Increased fasting insulin and triglycerides were associated with higher liver fat.
Takeaway
This study shows that having more fat around your belly can lead to more fat in your liver, but having fat in your thighs might help protect your liver.
Methodology
The study involved measuring body fat distribution using CT scans and assessing metabolic markers in 140 overweight and obese premenopausal Caucasian women.
Potential Biases
Potential bias due to the exclusion of women with certain health conditions and the reliance on self-reported physical activity.
Limitations
The study's findings may not be applicable to men or to women with different metabolic profiles, and the low prevalence of fatty liver in the sample limits generalizability.
Participant Demographics
140 overweight and obese premenopausal Caucasian women aged 25 to 49.
Statistical Information
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website