Health-related quality of life for pediatric emergency department febrile illnesses: an Evaluation of the Pediatric Quality of Life Inventory™ 4.0 generic core scales
2009

Evaluating Quality of Life in Children with Fever in Emergency Departments

Sample size: 160 publication 10 minutes Evidence: moderate

Author Information

Author(s): Rakesh D Mistry, Molly W Stevens, Marc H Gorelick

Primary Institution: Children's Hospital of Philadelphia

Hypothesis

The study aims to assess the validity and responsiveness of the Pediatric Quality of Life Inventory™ 4.0 for febrile illnesses in pediatric emergency departments.

Conclusion

The PedsQL™ is a valid and responsive measure of health-related quality of life for short-term febrile illnesses in the emergency department.

Supporting Evidence

  • The mean total HRQOL score improved from 76.4 at ED presentation to 86.3 at follow-up.
  • Statistically significant differences in HRQOL were noted for those with prolonged fever and functional impairment.
  • A significant correlation was observed between HRQOL at follow-up and days of daycare/school missed.

Takeaway

This study looked at how sick kids feel when they have a fever and found a way to measure their quality of life using a special questionnaire.

Methodology

A prospective cohort study of children aged 2-18 years discharged after ED evaluation for fever, using parent-reported health-related quality of life assessments.

Potential Biases

Potential observer and recall bias due to reliance on parental self-report for health assessments.

Limitations

The study had a 39% loss to follow-up, which may introduce selection bias, and missing item responses were more likely in the school functioning scale.

Participant Demographics

{"age_mean":"58.7 months","male_percentage":56,"race_ethnicity":{"white":47.4,"black":33.0,"hispanic":18.6,"other":1.0}}

Statistical Information

P-Value

p = .003

Confidence Interval

95% CI: 5.6–14.6

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1477-7525-7-5

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