Effective Control of Postprandial Glucose Level through Inhibition of Intestinal Alpha Glucosidase by Cymbopogon martinii (Roxb.)
2012

Controlling Blood Sugar with Cymbopogon martinii

Sample size: 6 publication Evidence: moderate

Author Information

Author(s): Varsha Ghadyale, Shrihari Takalikar, Vivek Haldavnekar, Akalpita Arvindekar

Primary Institution: Shivaji University, Kolhapur

Hypothesis

Cymbopogon martinii can effectively inhibit intestinal alpha glucosidase to control postprandial glucose levels in diabetic rats.

Conclusion

Cymbopogon martinii is a more effective alpha glucosidase inhibitor than acarbose at lower concentrations.

Supporting Evidence

  • Cymbopogon martinii showed 98% inhibition of maltase activity.
  • The study demonstrated better blood glucose control with Cymbopogon martinii compared to acarbose.
  • Cymbopogon martinii was effective at a concentration of 5 mg/kg body weight, while acarbose required 60 mg/kg.

Takeaway

This study shows that a grass called Cymbopogon martinii can help keep blood sugar levels down after meals, even better than a common diabetes medicine.

Methodology

The study involved in vitro and in vivo experiments using diabetic rats to assess the alpha glucosidase inhibitory activity of Cymbopogon martinii.

Limitations

The study was conducted on a small sample size of rats, and results may not directly translate to humans.

Participant Demographics

Adult male albino rats weighing between 200 ± 20 g.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1155/2012/372909

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