EPIC-DB: a proteomics database for studying Apicomplexan organisms
2009

EPIC-DB: A Database for Proteomics of Apicomplexan Organisms

publication Evidence: high

Author Information

Author(s): Madrid-Aliste Carlos J, Dybas Joseph M, Angeletti Ruth Hogue, Weiss Louis M, Kim Kami, Simon Istvan, Fiser Andras

Primary Institution: Albert Einstein College of Medicine

Conclusion

EPICDB is a comprehensive database that organizes and displays proteomics data for T. gondii and C. parvum, facilitating the analysis of their entire proteomes.

Supporting Evidence

  • EPICDB contains high throughput mass spectrometry data cross-referenced to all available protein sequences for T. gondii and C. parvum.
  • The database allows for the evaluation of redundancy and protein prediction discrepancies.
  • EPICDB includes data from 183 mass spectrometry experiments for T. gondii and 88 for C. parvum.

Takeaway

EPICDB is like a big library that helps scientists find and study proteins from two tiny germs that can make people sick.

Methodology

The database was constructed using a MySQL system and includes data from high throughput mass spectrometry experiments.

Limitations

The database may contain redundancy due to multiple gene prediction algorithms and experimental data.

Digital Object Identifier (DOI)

10.1186/1471-2164-10-38

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