Effects of HMB Supplementation on Muscle Damage
Author Information
Author(s): Wilson Jacob M, Kim Jeong-su, Lee Sang-rok, Rathmacher John A, Dalmau Brett, Kingsley J Derek, Koch Heather, Manninen Anssi H, Saadat Raz, Panton Lynn B
Primary Institution: Florida State University
Hypothesis
Consuming HMB prior to exercise would attenuate indices of muscle damage relative to both a placebo and consumption of HMB after exercise.
Conclusion
The study found no clear acute or timing effects of HMB supplementation on muscle damage, but taking HMB before exercise may prevent increases in certain damage markers.
Supporting Evidence
- HMB supplementation has been shown to lower exercise-induced muscle damage over longer periods.
- Participants who took HMB before exercise showed no significant increase in LDH levels after exercise.
- Muscle soreness peaked at different times for different groups, indicating varying effects of HMB timing.
Takeaway
This study looked at whether taking a supplement called HMB before or after exercise helps reduce muscle damage. It found that taking it before might help a little, but not a lot.
Methodology
Sixteen non-resistance trained men performed maximal eccentric knee contractions and were assigned to either HMB-Pre or HMB-Post groups in a crossover design.
Limitations
The study analyzed indirect indices of muscle damage, which may not fully capture the effects of HMB.
Participant Demographics
Sixteen healthy college-aged men, average age 22 years.
Statistical Information
P-Value
p = 0.07 for quadriceps soreness
Statistical Significance
p < 0.001
Digital Object Identifier (DOI)
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