Perinatal HIV transmission and the cost-effectiveness of screening at 14 weeks gestation, at the onset of labour and the rapid testing of infants
2008

Cost-Effectiveness of HIV Screening During Pregnancy

Sample size: 110000 publication Evidence: high

Author Information

Author(s): Udeh Belinda, Udeh Chiedozie, Graves Nicholas

Primary Institution: Public Policy Center, University of Iowa

Hypothesis

What are the cost-effectiveness and health benefits of different HIV screening strategies for pregnant women in the U.S. Virgin Islands?

Conclusion

Universal screening by 14 weeks gestation and screening the infant after birth is the most cost-effective strategy, saving over $1 million and generating 310 life years.

Supporting Evidence

  • All strategies produced health benefits and cost savings.
  • Universal screening by 14 weeks gestation is recommended.
  • The study suggests that not implementing universal screening is unethical.

Takeaway

Testing pregnant women for HIV early and again at birth can save lives and money. It's like checking if a plant needs water before it wilts and then again when it blooms.

Methodology

An economic model evaluated nine combinations of perinatal HIV screening strategies compared to existing practices.

Potential Biases

Potential bias in acceptance of testing based on specimen type and socioeconomic factors.

Limitations

Limited research on screening acceptance based on race and economic status; benefits of screening after 14 weeks were not addressed.

Participant Demographics

Population of around 110,000 with less than 70% receiving antenatal care in the first trimester.

Digital Object Identifier (DOI)

10.1186/1471-2334-8-174

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