Polarity-Dependent Transcranial Direct Current Stimulation Effects on Central Auditory Processing
2011

Effects of tDCS on Auditory Processing

Sample size: 11 publication 10 minutes Evidence: moderate

Author Information

Author(s): Ladeira Andrea, Fregni Felipe, Campanhã Camila, Valasek Cláudia Aparecida, De Ridder Dirk, Brunoni André Russwsky, Boggio Paulo Sérgio

Primary Institution: Mackenzie Presbyterian University, Sao Paulo, Brazil

Hypothesis

Anodal stimulation would increase performance on the Random Gap Detection Test (RGDT) and cathodal stimulation would decrease RGDT performance.

Conclusion

tDCS has a polarity-dependent effect on the temporal processing activity of the auditory cortex, improving performance during anodal stimulation and worsening it during cathodal stimulation.

Supporting Evidence

  • Anodal stimulation improved RGDT performance by 22.5% compared to baseline.
  • Cathodal stimulation decreased RGDT performance by 54.5% compared to baseline.
  • Significant effects were observed for the interaction of tDCS condition and time.

Takeaway

This study tested how a brain stimulation technique called tDCS affects how well people can hear and process sounds. It found that one type of stimulation helps, while another type makes it harder.

Methodology

A double-blinded, randomized, sham-controlled trial with 11 healthy subjects receiving anodal, cathodal, or sham tDCS while performing the Random Gap Detection Test.

Potential Biases

The study did not fully address multiple comparisons, which may introduce bias.

Limitations

The small sample size and the potential for multiple comparisons affecting results.

Participant Demographics

11 healthy young adults (5 men, mean age 21.36 years) with no hearing impairment.

Statistical Information

P-Value

p=0.04

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0025399

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