The Cytoskeleton in Papillomavirus Infection
2011
The Role of the Cytoskeleton in Papillomavirus Infection
publication
10 minutes
Evidence: moderate
Author Information
Author(s): Malgorzata Bienkowska-Haba, Martin Sapp
Primary Institution: Louisiana State University Health Sciences Center
Hypothesis
How do papillomaviruses utilize the host cytoskeleton during their infection process?
Conclusion
Recent advances have improved our understanding of how papillomaviruses interact with the host cell cytoskeleton during infection.
Supporting Evidence
- Papillomaviruses replicate in the basal cells of skin and mucosa.
- Viral entry involves the use of host cytoskeletal components.
- Recent studies suggest that HPV16 uses unique strategies for internalization.
Takeaway
Papillomaviruses need the cell's skeleton to help them get inside and spread, like using a slide to go down.
Methodology
This review summarizes recent findings on the interactions between papillomaviruses and host cytoskeletal elements.
Limitations
The study relies on existing literature and experimental models, which may not fully capture the complexities of natural infections.
Digital Object Identifier (DOI)
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