Understanding the Proteomes of the Bobtail Squid and Its Bacterium
Author Information
Author(s): Tyler R. Schleicher, Spencer V. Nyholm
Primary Institution: Department of Molecular and Cell Biology, University of Connecticut
Hypothesis
What are the contributions of the host and symbiont proteomes in the squid-Vibrio fischeri symbiosis?
Conclusion
The study identified 1581 unique proteins from both the squid and its symbiotic bacterium, revealing important roles in immune response and symbiosis regulation.
Supporting Evidence
- The study identified 870 symbiont proteins and 711 host proteins.
- Proteins related to the innate immune system were found in the host.
- Symbiont proteins involved in quorum sensing and detoxification were identified.
- The research provides the first proteomic analysis of the squid's light organ.
Takeaway
This study looked at the proteins in a squid and its bacteria to see how they help each other live together. They found a lot of important proteins that help keep the relationship healthy.
Methodology
Proteomic analyses using 1D- and 2D-polyacrylamide gel electrophoresis and multidimensional protein identification technology (MudPIT).
Digital Object Identifier (DOI)
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