Migraine and restless legs syndrome: is there an association?
2011

Migraine and Restless Legs Syndrome: Is There an Association?

publication Evidence: moderate

Author Information

Author(s): Paul R. Cannon, Andrew J. Larner

Primary Institution: Walton Centre for Neurology and Neurosurgery

Hypothesis

Is there a comorbidity between migraine and restless legs syndrome?

Conclusion

The evidence suggests that there is a significant association between migraine and restless legs syndrome.

Supporting Evidence

  • Several studies found a higher prevalence of restless legs syndrome in migraine patients compared to control groups.
  • One study reported that 34% of headache patients met the criteria for restless legs syndrome.
  • Another study found a statistically significant higher lifetime prevalence of restless legs syndrome in migraine patients (17.3%) compared to controls (5.6%).
  • Patients with migraine and restless legs syndrome had worse sleep quality scores compared to those with migraine alone.

Takeaway

This study looked at whether people with migraines also have restless legs syndrome, and it found that many do.

Methodology

A systematic review of existing studies on the association between migraine and restless legs syndrome was conducted.

Potential Biases

The use of selected populations and cross-sectional study designs may introduce bias.

Limitations

The studies reviewed had limitations such as small sample sizes and potential recall bias from patient questionnaires.

Participant Demographics

The studies included various patient demographics, but specific details were not provided.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1007/s10194-011-0357-x

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication