Pancreatic insulinoma co-existing with gastric GIST in the absence of neurofibromatosis-1
2009

Case of Pancreatic Insulinoma and Gastric GIST

Sample size: 1 publication Evidence: low

Author Information

Author(s): Alabraba Edward, Bramhall Simon, O'Sullivan Brendan, Mahon Brinder, Taniere Philippe

Primary Institution: University of Birmingham and UHB Foundation NHS Trust

Hypothesis

Can a pancreatic insulinoma co-exist with a gastric GIST in a patient without neurofibromatosis type 1?

Conclusion

This case report presents the first instance of a pancreatic insulinoma co-existing with a GIST in a patient without NF-1.

Supporting Evidence

  • This is the first case report of a pancreatic insulinoma co-existing with a GIST in a patient without NF-1.
  • The GIST was only discovered incidentally during surgery for the insulinoma.
  • The patient experienced rapid recurrence of the GIST after its initial resection.

Takeaway

A woman had a rare combination of two types of tumors: one in her pancreas and another in her stomach, and she didn't have a common genetic condition that usually causes these tumors.

Methodology

The patient underwent a series of tests including CT scans and surgery for tumor removal.

Limitations

The GIST was discovered incidentally and the mutation analysis was unsuccessful due to poor DNA quality.

Participant Demographics

76-year-old woman

Digital Object Identifier (DOI)

10.1186/1477-7819-7-18

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