Anti-inflammatory effects of KHU14 herbal formulation
Author Information
Author(s): Kim Kyoung Soo, Rhee Hae In, Park Eun Kyung, Jung Kiwon, Jeon Hyo Jin, Kim Ji-Hong, Yoo Hunseung, Han Chang-Kyun, Cho Yong-Baik, Ryu Chun Jeih, Yang Hyung In, Yoo Myung Chul
Primary Institution: Kyung Hee University Neo Medical Hospital
Hypothesis
KHU14, a formulation of three herbs, has anti-inflammatory effects in animal models.
Conclusion
KHU14 exhibited significant anti-inflammatory effects in various animal models.
Supporting Evidence
- KHU14 reduced ear thickness by 20% compared to the control group.
- KHU14 reduced paw edema by 38% in the carrageenan-induced model.
- KHU14 inhibited the production of NO and PGE2 in macrophages.
Takeaway
KHU14 is a mix of three herbs that helps reduce swelling and inflammation in animals.
Methodology
The study tested KHU14 in various animal models for its anti-inflammatory effects, including ear and paw edema tests.
Limitations
The study primarily used animal models, which may not fully represent human responses.
Participant Demographics
Female BALB/c mice and male ICR and Wistar rats, aged 5-6 weeks.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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