Pathophysiological lessons from rare associations of immunological disorders
2009

Lessons from Rare Immunological Disorders in Kidney Disease

Editorial Evidence: low

Author Information

Author(s): Ronco Pierre, Debiec Hanna

Primary Institution: Institut National de la Santé et de la Recherche Médicale (INSERM)

Hypothesis

Can rare associations of immunological disorders provide insights into the pathogenesis of kidney diseases?

Conclusion

Rare associations of immunological disorders can reveal important insights into the mechanisms of kidney diseases like membranous nephropathy and minimal change disease.

Supporting Evidence

  • Rare associations of immunological disorders can provide important clues to the pathogenesis of MN and MCD.
  • Cases of glomerular disease with thyroiditis and Graves’ disease have been reported.
  • Evidence suggests T-cell involvement in the pathogenesis of proteinuria.

Takeaway

Sometimes, looking at rare diseases can help doctors understand how common kidney problems happen. It's like finding clues in a mystery!

Potential Biases

Potential bias due to reliance on case reports rather than larger studies.

Limitations

The editorial discusses isolated case reports, which may not represent broader trends.

Digital Object Identifier (DOI)

10.1007/s00467-008-1009-5

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication