New algorithm improves fine structure of the barley consensus SNP map
2011

New Algorithm Improves Barley SNP Map

Sample size: 3000 publication Evidence: high

Author Information

Author(s): Jeffrey B Endelman

Primary Institution: Washington State University

Hypothesis

Can a new algorithm improve the accuracy of consensus SNP maps in barley?

Conclusion

The R package DAGGER produces a more accurate consensus map for barley than previous methods.

Supporting Evidence

  • DAGGER produced a consensus map with improved fine structure compared to the existing barley consensus SNP map.
  • The RMS error between the linkage maps and the DAGGER map was 0.82 cM per marker interval.
  • DAGGER is a freely available resource for integrating information from consistent linkage maps.

Takeaway

Scientists created a new tool called DAGGER that helps make better maps of barley genes, which can help in plant breeding.

Methodology

DAGGER uses linear and quadratic programming to create consensus maps from multiple linkage maps.

Statistical Information

P-Value

<10-4

Statistical Significance

p<10-4

Digital Object Identifier (DOI)

10.1186/1471-2164-12-407

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