Antimicrobial and Toxicological Activities of Five Medicinal Plants from Cameroon
Author Information
Author(s): Assob Jules CN, Kamga Henri LF, Nsagha Dickson S, Njunda Anna L, Nde Peter F, Asongalem Emmanuel A, Njouendou Abdel J, Sandjon Bertrand, Penlap Veronique B
Primary Institution: University of Buea
Hypothesis
The study aims to investigate the in vitro antimicrobial activity of extracts from five Cameroonian medicinal plants against various pathogenic microorganisms.
Conclusion
The study found that the extracts of the five medicinal plants can be used as effective antimicrobial agents against infections caused by multiresistant microorganisms.
Supporting Evidence
- The methanolic and ethylacetate extracts of Phyllanthus muellerianus and Piptadeniastum africana showed the highest antimicrobial activities.
- All plant extracts exhibited antibacterial and anticandidal activities.
- The acute toxicity study indicated that the extracts were not toxic at therapeutic doses.
Takeaway
This study shows that some plants from Cameroon can help fight germs that make people sick, and they don't harm the body when used properly.
Methodology
The study used agar well-diffusion and microdilution methods to test the antimicrobial activity of plant extracts on various bacteria and fungi.
Potential Biases
Potential bias may arise from the selection of plant species and the specific extraction methods used.
Limitations
The study primarily focused on in vitro results and did not assess long-term effects or clinical outcomes in humans.
Participant Demographics
The study involved Wistar albino rats for toxicity testing.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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