Randomized, placebo-controlled, double-blind trial of Swedish snus for smoking reduction and cessation
2011

Swedish Snus for Smoking Reduction and Cessation

Sample size: 319 publication 10 minutes Evidence: moderate

Author Information

Author(s): Gordana Joksić, Vera Spasojević-Tišma, Ruza Antić, Robert Nilsson, Lars E. Rutqvist

Primary Institution: Vinča Institute of Nuclear Sciences, University of Belgrade, Serbia

Hypothesis

Can Swedish snus help adult cigarette smokers in Serbia reduce and eventually stop smoking?

Conclusion

Swedish snus could promote smoking cessation among smokers in Serbia.

Supporting Evidence

  • Participants in the snus group reported higher rates of smoking reduction compared to the placebo group.
  • At week 24, 63.9% of the snus group achieved a ≥ 50% smoking reduction.
  • The odds of quitting smoking completely were higher in the snus group at various time points.
  • Snus was well tolerated with a low discontinuation rate due to adverse events.

Takeaway

This study tested if a type of tobacco called Swedish snus could help people in Serbia quit smoking. It found that snus might help some people stop smoking completely.

Methodology

A randomized, double-blind, placebo-controlled trial with 319 participants over 48 weeks.

Potential Biases

Potential bias due to lack of experience with smoking cessation interventions at study centers.

Limitations

The study centers had no previous experience with smoking cessation programs, which may have affected the quit rates.

Participant Demographics

Participants were healthy smokers aged 20-65, with 61% female and an average age of 44 years.

Statistical Information

P-Value

0.04-0.10

Confidence Interval

1.9 to 3.4

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1186/1477-7517-8-25

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication