Correlation of LNCR rasiRNAs Expression with Heterochromatin Formation during Development of the Holocentric Insect Spodoptera frugiperda
2011

Study of LNCR rasiRNAs and Heterochromatin in Spodoptera frugiperda

publication 10 minutes Evidence: moderate

Author Information

Author(s): Stanojcic Slavica, Gimenez Sylvie, Permal Emmanuelle, Cousserans François, Quesneville Hadi, Fournier Philippe, d'Alençon Emmanuelle

Primary Institution: UMR1333 INRA, Université Montpellier II, Montpellier, France

Hypothesis

The expression of LNCR rasiRNAs is developmentally regulated and correlates with heterochromatin formation in Spodoptera frugiperda.

Conclusion

The study found that increased expression of LNCR rasiRNAs is linked to the accumulation of heterochromatic marks during the development of Spodoptera frugiperda.

Supporting Evidence

  • LNCR rasiRNAs are developmentally regulated and correlate with heterochromatin formation.
  • Expression of LNCR and LNCR rasiRNAs peaks at specific developmental stages.
  • ChIP analysis shows dynamic changes in histone modifications during development.

Takeaway

This study shows that certain tiny RNA molecules help control how genes are turned on and off during the growth of a pest insect, which can affect its development.

Methodology

The study involved deep sequencing of small RNAs from different developmental stages of Spodoptera frugiperda and chromatin immunoprecipitation to analyze histone modifications.

Limitations

The study is limited by the incomplete genomic data of Spodoptera frugiperda, which restricts the identification of all rasiRNAs.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0024746

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