Treatment Outcomes and Cost-Effectiveness of Shifting Management of Stable ART Patients to Nurses in South Africa: An Observational Cohort
2011

Cost-Effectiveness of Nurse-Managed ART for Stable HIV Patients in South Africa

Sample size: 2848 publication 10 minutes Evidence: high

Author Information

Author(s): Lawrence Long, Alana Brennan, Matthew P. Fox, Buyiswa Ndibongo, Imogen Jaffray, Ian Sanne, Sydney Rosen

Primary Institution: Health Economics and Epidemiology Research Office, Wits Health Consortium, Johannesburg, South Africa

Hypothesis

Shifting management of stable ART patients from doctors to nurses will provide comparable health outcomes and lower costs.

Conclusion

Down-referring stable ART patients to nurse-managed clinics results in better health outcomes and lower costs compared to hospital-based doctor-managed care.

Supporting Evidence

  • Down-referred patients had a 1.7% death rate compared to 6.2% for those who remained in hospital care.
  • The average cost per patient-year was $492 for down-referred patients versus $551 for those in hospital care.
  • 95.5% of down-referred patients remained in care and responding after 12 months.

Takeaway

This study shows that having nurses take care of stable HIV patients is cheaper and just as effective as having doctors do it.

Methodology

The study compared outcomes and costs of stable ART patients down-referred from a doctor-managed clinic to a nurse-managed primary health clinic.

Potential Biases

Potential unmeasured factors may have influenced outcomes between the two patient groups.

Limitations

The study was conducted at only one pair of sites, which may not be representative of other facilities in South Africa.

Participant Demographics

{"mean_age":38.5,"sex_percent_female":65.4}

Statistical Information

P-Value

p<0.0001

Confidence Interval

95% CI 0.15–0.49

Statistical Significance

p<0.0001

Digital Object Identifier (DOI)

10.1371/journal.pmed.1001055

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