Allylsilanes in the synthesis of three to seven membered rings: the silylcuprate strategy
2007

Using Allylsilanes to Create Rings in Organic Chemistry

publication Evidence: moderate

Author Information

Author(s): Barbero Asunción, Pulido Francisco J, Sañudo M Carmen

Primary Institution: Universidad de Valladolid

Hypothesis

The silylcuprate strategy can provide new routes for the synthesis of functionalized allylsilanes that lead to the formation of three to seven membered rings.

Conclusion

The metallocupration of allenes and acetylenes is effective for constructing cyclic structures ranging from three to seven membered rings.

Supporting Evidence

  • Allylsilanes can be synthesized using silylcuprates and electrophiles.
  • The reactions lead to a variety of cyclic structures.
  • Different electrophiles can influence the size and type of the rings formed.

Takeaway

This study shows how certain chemicals can be used to make small rings in organic compounds, which can be really useful for creating new materials.

Methodology

The study reviews recent advances in allylsilane chemistry and their applications in synthesizing cyclic structures.

Limitations

The study does not address the efficiency of all possible reagents for the reactions discussed.

Digital Object Identifier (DOI)

10.1186/1860-5397-3-16

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