IGOB131, a novel seed extract of the West African plant Irvingia gabonensis, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controlled investigation
2009

Effects of Irvingia gabonensis Extract on Weight and Metabolic Health

Sample size: 102 publication 10 minutes Evidence: moderate

Author Information

Author(s): Ngondi Judith L, Etoundi Blanche C, Nyangono Christine B, Mbofung Carl MF, Oben Julius E

Primary Institution: Laboratory of Nutrition and Nutritional Biochemistry, Faculty of Science, University of Yaounde I, Yaounde, Cameroon

Hypothesis

Does IGOB131, an extract of Irvingia gabonensis, reduce body weight and improve metabolic parameters in overweight humans?

Conclusion

The study found that Irvingia gabonensis extract significantly reduces body weight and improves various metabolic parameters in overweight individuals.

Supporting Evidence

  • Participants taking IGOB131 lost significantly more weight than those on placebo.
  • IGOB131 improved metabolic parameters like cholesterol and blood glucose levels.
  • The study was conducted over 10 weeks with regular monitoring of health metrics.

Takeaway

This study shows that a seed extract from a West African fruit can help people lose weight and improve their health.

Methodology

The study was a randomized, double-blind, placebo-controlled trial with 102 overweight participants receiving either IGOB131 or placebo for 10 weeks.

Potential Biases

Potential bias due to funding from a company that provided the extract.

Limitations

The study had a dropout rate of 15% and was limited to a specific demographic in Cameroon.

Participant Demographics

120 participants (62 males, 58 females) aged 19 to 50, all overweight or obese.

Statistical Information

P-Value

p<0.01

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1476-511X-8-7

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