Effect of plant sterols on the lipid profile of patients with hypercholesterolaemia. Randomised, experimental study
2011

Effect of Plant Sterols on Cholesterol Levels in Patients with High Cholesterol

Sample size: 182 publication Evidence: moderate

Author Information

Author(s): Párraga Ignacio, López-Torres Jesús, Andrés Fernando, Navarro Beatriz, del Campo José M, García-Reyes Mercedes, Galdón María P, Lloret Ángeles, Precioso Juan C, Rabanales Joseba

Primary Institution: Research Unit, Primary Care Head Office of Albacete, Health Care Service of Castilla-La Mancha

Hypothesis

Does the intake of 2 g of plant sterol esters daily lower LDL-cholesterol levels in patients with hypercholesterolaemia?

Conclusion

The study aims to determine if plant sterol esters can effectively lower LDL-cholesterol levels in patients with high cholesterol.

Supporting Evidence

  • Plant sterols can lower cholesterol levels similarly to statins.
  • Daily intake of 2 g of plant sterols is recommended for cholesterol reduction.
  • Few long-term studies exist on the effects of plant sterols in Spanish populations.

Takeaway

This study is trying to find out if eating a special yogurt with plant sterols can help people with high cholesterol lower their bad cholesterol levels.

Methodology

Randomised, double-blind, placebo-controlled trial over 24 months with adults diagnosed with hypercholesterolaemia.

Potential Biases

There may be risks of bias in data collection and differential loss to follow-up between groups.

Limitations

The study may face issues with participant dropout and potential biases in self-reported data.

Participant Demographics

Adults diagnosed with limit or defined hypercholesterolaemia, aged 18 and over.

Digital Object Identifier (DOI)

10.1186/1472-6882-11-73

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