Claudins in lung diseases
2011

Claudins in Lung Diseases

publication

Author Information

Author(s): Ylermi Soini

Primary Institution: University of Eastern Finland

Conclusion

Claudins play a significant role in the permeability of tight junctions in lung diseases, influencing how pathogens and other substances interact with lung tissues.

Supporting Evidence

  • Tight junctions are crucial for lung defense as they prevent pathogens from penetrating lung tissues.
  • Claudins are involved in the regulation of paracellular permeability in lung cells.
  • Changes in claudin expression are associated with various lung diseases, including asthma and ARDS.

Takeaway

Claudins are proteins that help keep the lungs safe by controlling what can pass through cell layers, and changes in these proteins can lead to lung diseases.

Digital Object Identifier (DOI)

10.1186/1465-9921-12-70

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