Vaginal Microbiota of Healthy Pregnant Mexican Women
Author Information
Author(s): César Hernández-Rodríguez, Roberto Romero-González, Mario Albani-Campanario, Ricardo Figueroa-Damián, Noemí Meraz-Cruz, César Hernández-Guerrero
Primary Institution: Instituto Politécnico Nacional
Hypothesis
To identify the microbiota communities in the vaginal tracts of healthy Mexican women across the pregnancy.
Conclusion
Lactobacillus genus predominates in the vaginal samples of Mexican pregnant women associated with different microorganisms related to bacterial vaginosis conditions.
Supporting Evidence
- Lactobacillus genus was present in 98% of women studied.
- Four lactobacilli species were identified: L. acidophilus, L. iners, L. gasseri, and L. delbrueckii.
- 17 different microorganisms related to bacterial vaginosis conditions were identified.
- Ureaplasma urealyticum was the predominant microorganism related to bacterial vaginosis.
Takeaway
This study looked at the bacteria in the vaginas of healthy pregnant women in Mexico and found that most had good bacteria called Lactobacillus, which helps keep them healthy.
Methodology
Vaginal swabs were obtained from healthy pregnant women, and DNA was isolated and analyzed using PCR-DGGE and sequencing of 16S rRNA gene fragments.
Potential Biases
Potential bias in sample selection as only women without symptoms or recent antimicrobial therapy were included.
Limitations
The study only included women with Nugent scores of 0-3, which may not represent all pregnant women.
Participant Demographics
Mean maternal age was 27.5 years, with samples collected from women in all three trimesters of pregnancy.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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