Heterotopic ossification after patellar tendon repair in a man with trisomy 8 mosaicism: a case report and literature review
2011

Heterotopic ossification after patellar tendon repair in a man with trisomy 8 mosaicism

Sample size: 1 publication Evidence: low

Author Information

Author(s): Chen Austin, Chmell Samuel

Primary Institution: University of Illinois at Chicago

Hypothesis

Is there an association between trisomy 8 mosaicism and increased risk of heterotopic ossification after patellar tendon repair?

Conclusion

This case suggests a possible link between trisomy 8 mosaicism and the development of heterotopic ossification following patellar tendon repair.

Supporting Evidence

  • There are no prior reports of heterotopic ossification as a complication of patellar tendon repair.
  • The patient's T8M status may have increased his risk for developing heterotopic ossification postoperatively.
  • Chromosome 8 has been linked to certain bone morphogenetic proteins that may explain abnormal bone formation.

Takeaway

A man with a rare genetic condition had a problem where his body made extra bone in the wrong places after knee surgery, which is not usually seen in such cases.

Methodology

Case report detailing the patient's history, surgical procedure, and follow-up observations.

Limitations

Only one case is reported, limiting generalizability.

Participant Demographics

32-year-old African-American man with trisomy 8 mosaicism.

Digital Object Identifier (DOI)

10.1186/1752-1947-5-453

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