Vitamin D and Prostate Health in Men
Author Information
Author(s): Muacevic Alexander, Adler John R, Reddy Janvitha, K A Arul Senghor, V M Vinodhini, Prasath N, Ravat Mansi
Primary Institution: Sri Ramaswamy Memorial Medical College Hospital and Research Centre
Hypothesis
This study aimed to investigate the association of vitamin D with prostate health status in men and determine the diagnostic cut-off of vitamin D levels.
Conclusion
Vitamin D deficiency is a potential biochemical marker of benign prostate hypertrophy, and screening of total PSA levels reflects prostate health status in men.
Supporting Evidence
- Total PSA levels significantly increased in men over 75 years of age.
- Vitamin D-deficient individuals had significantly increased total PSA levels.
- A significant negative correlation of total PSA with vitamin D levels was found.
- ROC analysis revealed a diagnostic sensitivity of 86% and specificity of 60% for vitamin D at a cut-off of 20 ng/ml.
Takeaway
This study found that not having enough vitamin D might be linked to prostate problems in men, and checking PSA levels can help understand prostate health.
Methodology
This analytical cross-sectional study involved men aged 45 to 80 years with urinary complaints, categorized by total PSA levels, and analyzed vitamin D levels using ELISA.
Limitations
The study had a small sample size and was cross-sectional, limiting the generalizability and long-term insights.
Participant Demographics
Men aged 45 to 80 years with urinary complaints.
Statistical Information
P-Value
0.022
Statistical Significance
p=0.022
Digital Object Identifier (DOI)
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