Prevalence of HIV-2 in Maputo, Mozambique
Author Information
Author(s): Maueia Cremildo, Costa Deise, Meggi Bindiya, Ismael Nalia, Walle Carla, Curvo Raphael, Abreu Celina, Bhatt Nilesh, Tanuri Amilcar, Jani Ilesh V, Ferreira Orlando C Jr
Primary Institution: Instituto Nacional de Saúde, Maputo, Moçambique
Hypothesis
Population migration and mobility in Africa may have facilitated the introduction and spreading of HIV-2 in Mozambique.
Conclusion
The study found a low prevalence of HIV-2 (0.25%) among HIV positive individuals in Maputo City.
Supporting Evidence
- The presence of HIV-2 has important implications for diagnosis and treatment.
- Only three specimens were found to be positive for HIV-2 subtype A.
- The majority of the HIV epidemic in Southern Mozambique is driven by HIV-1.
Takeaway
Researchers looked at how many people in Maputo have HIV-2, a type of HIV that is less common than HIV-1, and found that only a few had it.
Methodology
A cross-sectional study was conducted with 1,200 HIV-infected individuals who were screened for HIV-2 using enzyme immunoassays and PCR.
Potential Biases
Potential bias in sample selection as participants were recruited from a single outpatient clinic.
Limitations
The study may not represent the entire population of Mozambique due to its focus on a specific city and clinic.
Participant Demographics
HIV-infected individuals attending an outpatient clinic in Maputo City.
Statistical Information
P-Value
0.25
Confidence Interval
90% CI 0.01-0.49
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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